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Metoprolol should not be used in the event of: Stimulus conduction disorders from the atria to the ventricles (2nd and 3rd degree AV block).
Sick sinus syndrome.
Disordered stimulus conduction between sinus nodes and atria (high-grade SA blocks).
Shock.
(Manifest) myocardial insufficiency.
A resting pulse rate before therapy of less than 50 beats per minute (bradycardia).
Pathologically low blood pressure (hypotension).
Superacidity of the blood (acidosis).
Late stages of peripheral circulatory disturbance.
Tendency to bronchial spasms (bronchial hyper-reactivity).
Concurrent administration of MAO inhibitors (except MAO-B inhibitors)
Known hypersensitivity to Metoprolol and related derivatives.
